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Top 25 Best Spa Retreats USA for Ultimate Relaxation

The wellness tourism industry in the United States has experienced remarkable growth in recent years, with more travelers seeking rejuvenating escapes from their busy lives. According to the Global Wellness Institute, wellness tourism is now a $651 billion industry globally, with the USA leading as a premier destination for luxury spa retreats.

Whether you’re looking to detox in desert hot springs, find serenity in mountain landscapes, or indulge in coastal relaxation, the best spa retreats USA has to offer combine stunning natural settings with world-class treatments. From traditional therapies to cutting-edge wellness technologies, these destinations provide transformative experiences for mind, body, and spirit.

We’ve curated this comprehensive guide to the top 25 wellness and spa retreats across the United States, organized by region to help you find your perfect sanctuary for relaxation and renewal.

Essential Preparation for Your Spa Retreat Experience

Before embarking on your wellness journey to one of the best spa retreats USA offers, proper preparation can enhance your experience. Pack light, comfortable clothing for various activities and treatments. Consider bringing your eco-friendly Yoga Mat for sunrise sessions or meditation practices offered at many retreats.

Many wellness experts recommend bringing a personal Essential Oils Set to complement your spa treatments. Lavender can enhance sleep quality, while eucalyptus can deepen breathing exercises in steam rooms. These personal touches can elevate your retreat experience and help maintain your wellness routine after returning home.

Pro Tip: Most luxury spa retreats provide robes, slippers, and toiletries, but always check with your specific destination about what amenities are included in your stay.

West Coast: Best Spa Retreats USA Has to Offer

The Pacific coastline provides a stunning backdrop for some of America’s most luxurious wellness destinations, combining ocean views with innovative treatments.

Aerial view of Omni La Costa Resort in Carlsbad, California

1. Omni La Costa Resort & Spa – Carlsbad, California

This historic Spanish Colonial-style resort has been a wellness destination since 1965, offering the first full-service spa in America. The Chopra Center for Wellbeing, founded by Deepak Chopra, provides Ayurvedic treatments and meditation programs.

Signature Amenities: Reflexology pathway, Roman waterfall showers, herb garden, championship golf courses

Pricing: $$$$ | Luxury

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Oceanfront view of Hotel del Coronado spa in San Diego

2. Hotel del Coronado – San Diego, California

This iconic beachfront property has hosted celebrities and royalty for over 130 years. The award-winning spa offers ocean-inspired treatments in a Victorian-inspired setting with modern amenities.

Signature Amenities: Beachfront spa cabanas, quartz sand therapy, hydrotherapy pools, private beach access

Pricing: $$$$ | Historic Luxury

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Fairmont Miramar Hotel & Bungalows spa treatment room in Santa Monica

3. Fairmont Miramar Hotel & Bungalows – Santa Monica, California

Serving Santa Monica since 1921, this award-winning coastal retreat offers the perfect blend of beach life and wellness. The Exhale Spa provides transformative therapies in a serene setting.

Signature Amenities: Barre and yoga classes, acupuncture, custom facials, oceanfront meditation

Pricing: $$$$ | Beachfront Luxury

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Desert Oasis: Rejuvenating Retreats in Arid Landscapes

The American Southwest offers unique healing environments where ancient traditions meet modern wellness practices against stunning desert backdrops.

Amangiri resort and spa pools with desert landscape in Utah

4. Amangiri – Canyon Point, Utah

Set among 600 acres of protected valley, this architectural marvel offers one of the best spa retreats USA has within its desert landscapes. The 25,000-square-foot spa draws inspiration from Navajo healing traditions.

Signature Amenities: Desert view sauna, step pool, flotation therapy pavilion, candlelit evening treatments

Pricing: $$$$$ | Ultra-Luxury

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Castle Hot Springs natural thermal pools in Arizona

5. Castle Hot Springs – Morristown, Arizona

Arizona’s first wellness resort (established 1896) centers around natural hot springs in the Sonoran Desert. This 1,100-acre oasis offers thermal waters rich in minerals that reach temperatures of 120°F naturally.

Signature Amenities: Three thermal pools, farm-to-table dining, desert adventures, digital detox environment (no TVs)

Pricing: $$$$ | Historic Luxury

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Sensei Porcupine Creek spa treatment room in Rancho Mirage

6. Sensei Porcupine Creek – Rancho Mirage, California

Founded by Oracle’s Larry Ellison and Dr. David Agus, this data-driven wellness retreat on a 230-acre estate combines cutting-edge technology with evidence-based practices for optimal wellbeing.

Signature Amenities: Personalized wellness evaluations, thermal wellness gardens, Nobu dining experiences, golf course

Pricing: $$$$$ | Tech-Forward Luxury

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Mountain Escapes: Elevated Wellness Experiences

The majestic mountain ranges across America provide serene backdrops for some of the most transformative spa experiences in the country.

The Broadmoor resort exterior with mountain backdrop in Colorado Springs

7. The Broadmoor – Colorado Springs, Colorado

This historic grande dame of the Rockies has been welcoming guests since 1918. The 43,000-square-foot spa combines European traditions with indigenous ingredients for a uniquely Colorado experience.

Signature Amenities: Mountain-view relaxation rooms, oxygen facials, CBD treatments, fireplace lounges

Pricing: $$$$ | Historic Luxury

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Omni Grove Park Inn spa waterfall and pools in Asheville

8. Omni Grove Park Inn – Asheville, North Carolina

Nestled in the Blue Ridge Mountains, this Arts and Crafts masterpiece houses one of the most unique subterranean spas in America, with cavernous rock walls and underwater music.

Signature Amenities: Mineral pools, contrast therapy waterfalls, fiber optic starlit ceiling, mountain views

Pricing: $$$$ | Historic Mountain Luxury

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Mohonk Mountain House exterior with lake view in New Paltz

9. Mohonk Mountain House – New Paltz, New York

This Victorian castle resort has been welcoming guests since 1869, with a 30,000-square-foot eco-friendly spa added in 2005. The stunning setting above a glacial lake in the Hudson Valley provides a perfect backdrop for renewal.

Signature Amenities: Solarium with stone fireplace, outdoor mineral pool, guided forest bathing, mindfulness in motion classes

Pricing: $$$$ | Historic Nature Immersion

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Eastern Seaboard: Coastal Wellness Destinations

The Atlantic coast offers elegant spa retreats that combine maritime traditions with innovative wellness approaches.

Inn at Perry Cabin waterfront view in St. Michaels, Maryland

10. Inn at Perry Cabin – St. Michaels, Maryland

This historic waterfront manor on the Chesapeake Bay combines maritime heritage with refined luxury. The Spa at Perry Cabin utilizes local botanicals and sea-inspired treatments.

Signature Amenities: Aromatic steam room, seaside meditation garden, sailing-inspired stretching classes, seasonal treatments

Pricing: $$$$ | Coastal Luxury

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The Don CeSar pink facade and beachfront in St. Pete Beach

11. The Don CeSar – St. Pete Beach, Florida

Known as Florida’s “Pink Palace,” this 1928 landmark offers Spa Oceana, a two-story sanctuary with treatments inspired by the healing properties of the sea and Mediterranean wellness traditions.

Signature Amenities: Rooftop garden terrace, couples’ treatments with Gulf views, seaweed wraps, Hammam rituals

Pricing: $$$$ | Historic Beach Luxury

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Wentworth Mansion spa treatment room in Charleston

12. Wentworth Mansion – Charleston, South Carolina

This 1886 Gilded Age mansion houses a spa within the property’s former stables, where original brick walls and arched windows create a unique atmosphere for treatments that blend Southern hospitality with European techniques.

Signature Amenities: Couples’ massage room with fireplace, garden-inspired treatments, custom aromatherapy blending

Pricing: $$$$ | Historic Boutique

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New England: Traditional Wellness Havens

New England’s rich history and natural beauty provide the perfect setting for wellness retreats that honor tradition while embracing innovation.

Miraval Berkshires resort exterior in Lenox, Massachusetts

13. Miraval Berkshires Resort & Spa – Lenox, Massachusetts

Part of the renowned Miraval brand, this mindfulness-focused retreat in the cultural heart of the Berkshires offers over 100 wellness activities and spa treatments designed to create life in balance.

Signature Amenities: Indoor/outdoor pools, challenge course, equine therapy, digital device-free zones

Pricing: $$$$$ | Mindfulness Luxury

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Kripalu Center for Yoga & Health exterior in Stockbridge

14. Kripalu Center for Yoga & Health – Stockbridge, Massachusetts

One of America’s most established yoga and wellness educational centers, Kripalu offers immersive programs ranging from weekend workshops to month-long trainings in a supportive community environment.

Signature Amenities: Daily yoga classes, silent breakfast, hiking trails, Ayurvedic consultations, whirlpool and sauna

Pricing: $$ | Educational Wellness

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Castle Hill Resort and Spa in winter in Cavendish, Vermont

15. Castle Hill Resort and Spa – Cavendish, Vermont

Set within Vermont’s Green Mountains, this historic Craftsman-style mansion combines old-world charm with modern spa amenities. The Aveda Concept Spa offers treatments that change with the seasons.

Signature Amenities: Heated indoor pool, hot tub, fitness center, seasonal outdoor activities, plant-based treatments

Pricing: $$$ | Historic Charm

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Southern Comfort: Wellness with Hospitality

The American South combines traditional hospitality with innovative wellness approaches in these standout destinations.

The Peabody Memphis hotel lobby with famous ducks

16. The Peabody Memphis – Memphis, Tennessee

This historic hotel, famous for its resident ducks, offers Feathers Spa, where Southern hospitality meets luxury treatments. The spa’s design draws inspiration from the hotel’s Art Deco heritage.

Signature Amenities: Couples’ suite with soaking tub, heated tile loungers, signature duck-shaped chocolates post-treatment

Pricing: $$$ | Historic Luxury

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French Lick Springs Hotel exterior and gardens in Indiana

17. French Lick Springs Hotel – French Lick, Indiana

Established in 1845 around the healing Pluto Mineral Springs, this historic resort offers a 27,000-square-foot spa that continues the tradition of mineral water therapies while adding modern treatments.

Signature Amenities: Mineral springs bathing, Pluto water treatments, sports massage therapy, natatorium

Pricing: $$$ | Historic Mineral Springs

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Blackburn Inn spa treatment room in Staunton, Virginia

18. The Blackburn Inn and Conference Center – Staunton, Virginia

This boutique hotel transformed from a historic building offers a unique spa experience that honors the property’s 80-acre campus with treatments inspired by the Shenandoah Valley’s natural bounty.

Signature Amenities: CBD treatments, couples’ massages, locally-sourced botanical products, garden relaxation areas

Pricing: $$$ | Boutique Historic

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Midwest Wellness: Heartland Healing

The American Midwest offers unexpected luxury and world-class spa experiences in these standout destinations.

The American Club exterior in Kohler, Wisconsin

19. The American Club – Kohler, Wisconsin

This five-star, five-diamond destination housed in a historic building offers Kohler Waters Spa, a leader in hydrotherapy treatments utilizing the company’s innovative plumbing fixtures in therapeutic ways.

Signature Amenities: Custom Vichy shower treatments, acoustic room, rooftop deck with whirlpool, water-inspired therapies

Pricing: $$$$ | Hydrotherapy Luxury

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The Pfister Hotel spa relaxation room in Milwaukee

20. The Pfister Hotel – Milwaukee, Wisconsin

This Victorian masterpiece known as the “Jewel of Milwaukee” houses WELL Spa + Salon, where 19th-century elegance meets contemporary treatments in a setting that honors the hotel’s artistic heritage.

Signature Amenities: Hammam steam room, couples’ massage suites, chromotherapy, seasonal treatments

Pricing: $$$ | Historic Elegance

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Palmer House hotel spa pool in Chicago

21. Palmer House, A Hilton Hotel – Chicago, Illinois

This historic Beaux-Arts hotel in downtown Chicago offers Balance Spa, where urban wellness meets historic luxury. The spa’s design pays homage to the hotel’s storied past while offering modern treatments.

Signature Amenities: CBD treatments, HydraFacial technology, indoor pool with Art Deco details, fitness center

Pricing: $$$ | Urban Historic

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Unique Wellness Experiences: Beyond Traditional Spas

These distinctive destinations offer wellness approaches that go beyond conventional spa treatments.

The Ranch Malibu hiking trail with ocean views

22. The Ranch Malibu – Malibu, California

This results-oriented wellness retreat offers an immersive boot camp-style program limited to 25 guests. The structured daily schedule includes hiking, fitness classes, massage, and plant-based nutrition.

Signature Amenities: Daily 4-hour mountain hikes, plant-based organic meals, body composition analysis, daily massage

Pricing: $$$$$ | Fitness Immersion

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The Art of Living Retreat Center meditation hall in North Carolina

23. The Art of Living Retreat Center – Boone, North Carolina

Set on 380 acres in the Blue Ridge Mountains, this retreat focuses on Ayurvedic treatments, meditation, and breathwork in a community-oriented setting that encourages personal transformation.

Signature Amenities: Panchakarma detox programs, Shirodhara therapy, silent retreats, pottery classes, labyrinth

Pricing: $$ | Spiritual Wellness

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Equinox Hotel sleep lab room in New York City

24. Equinox Hotel – New York City, New York

This fitness brand’s first hotel focuses on sleep optimization with specialized sleep lab rooms featuring temperature regulation, soundproofing, and total darkness technologies alongside a comprehensive spa and fitness center.

Signature Amenities: Cryotherapy chambers, infrared sauna, quantum harmonics sessions, sleep coaching, IV drips

Pricing: $$$$$ | Performance Wellness

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Island Escapes: Tropical Wellness Havens

These island destinations offer the ultimate combination of tropical paradise and wellness expertise.

Little Palm Island Resort beachfront spa cabana in Florida Keys

25. Little Palm Island Resort & Spa – Little Torch Key, Florida

This private island resort accessible only by boat or seaplane offers SpaTerre, where Indonesian and Thai influences combine with tropical ingredients in an adults-only paradise setting.

Signature Amenities: Outdoor shower gardens, couples’ treatments in seaside cabanas, Thai massage, custom aromatherapy

Pricing: $$$$$ | Private Island Luxury

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How to Choose the Perfect Spa Retreat

Woman researching spa retreats on laptop with notebook

When selecting from the best spa retreats USA has to offer, consider these factors to ensure your wellness journey aligns with your personal needs:

Wellness Goals

  • Stress reduction and relaxation
  • Fitness and weight management
  • Spiritual growth and mindfulness
  • Detoxification and cleansing
  • Medical wellness and health optimization

Practical Considerations

  • Budget and value expectations
  • Preferred location and climate
  • Length of stay (weekend vs. week-long)
  • Solo travel or with partner/group
  • Specific dietary requirements

Ready for Your Wellness Journey?

Pack your eco-friendly yoga mat and essential oils and book your perfect retreat today. Many properties offer seasonal specials and wellness packages for additional value.

Explore Top Retreats Now

Embracing Wellness: The Future of Spa Retreats

The best spa retreats USA offers continue to evolve, incorporating new technologies, ancient wisdom, and personalized approaches to wellness. From the coastal elegance of California to the mountain serenity of the Blue Ridge, these destinations provide sanctuaries for rejuvenation in our increasingly fast-paced world.

Whether you seek a digital detox, fitness reboot, spiritual connection, or simply luxurious pampering, America’s diverse landscape of wellness retreats offers something for every seeker. The transformative power of these experiences extends far beyond your stay, inspiring healthier habits and renewed perspective long after you return home.

As wellness tourism continues its remarkable growth, these top 25 destinations represent the pinnacle of American spa experiences—places where natural beauty, exceptional service, and healing traditions combine to create truly unforgettable journeys toward wellbeing.

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